Therapeutic potential of Yersinia anti-inflammatory components

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Abstract

Microbial pathogens have developed various stratagems for modulating and/or circumventing the host's innate and adaptive immunity. Hence, certain virulence factors can be viewed as potential therapeutic agents for human immunopathological diseases. This is the case for virulence plasmid-encoded proteins from pathogenic Yersiniae that inhibit the host's inflammatory response by interfering with various cellular signaling pathways. © 2007 Springer Science+Business Media, LLC.

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Foligné, B., Dewulf, J., Pot, B., Daniel, C., Simonet, M., Poiret, S., … Dessein, R. (2007). Therapeutic potential of Yersinia anti-inflammatory components. In Advances in Experimental Medicine and Biology (Vol. 603, pp. 361–366). Springer New York. https://doi.org/10.1007/978-0-387-72124-8_33

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