Radiogenomics as association between non-invasive imaging features and molecular genomics of lung cancer

Abstract

Cancer is a genetic disease caused by changes to genes controlling the way our cells function, mainly how they grow and divide. Lung cancer is a heterogeneous family of tumors, whose most common type is adenocarcinoma. In 2011, the International Association for the Study of Lung Cancer, the American Thoracic Society and the European Respiratory Society published a multidisciplinary classification of lung adenocarcinoma (1), with further refinements introduced in the World Health Organization (WHO) classification of 2015, integrating genetic and molecular data (2).