Reverse T3 Dilemma

Abstract

In recent years thyroid dysfunction became a popular topic as the cause of unexplained symptoms and chronic illnesses. There are many “cures” provided online and in multiple books marketed to the public. One common controversy is the “reverse T3 syndrome” in which patients with symptoms suggestive of thyroid disease will present with an elevated rT3 and otherwise normal thyroid function tests. Proponents of the “rT3 syndrome” suggest treating this condition with T3. Additionally, patients will come to their health-care provider with knowledge of thyroid physiology and pathophysiology and expect specific lab testing and treatments which they believe are the answer to all the ailments. It is our duty to educate the patient on the research and knowledge that we have and explore the treatment options that are appropriate for the patient and, more importantly, prevent harm to patients during their search for a “cure.”