Syntheses and characterizations of two novel silver polymers from assembly 5-bromosalicylic acid and 2-aminobenzoic acid, with high inhibitory activities against Jack Bean urease

Abstract

Two novel two-dimensional silver(I) polymers, [Ag(5-bsa)]n (1) and [Ag(2-aba)]n (2) (5-bsaH = 5-bromosalicylic acid and 2-abaH = 2-aminobenzoic acid), have been synthesized from the reaction of Ag2O and carboxylate ligands in ammonia solution and structurally determined by single-crystal X-ray diffraction analyses. 1 crystallizes in the monoclinic space group P21/c with a = 7.316(2), b = 8.171(2), c = 13.051(3) Å, U = 777.0(3) Å3, β = 95.14(3) and Z = 4. 2 crystallizes in the orthorhombic space group Pna21, with a = 5.9486(8), b = 24.227(3), c = 4.9042(6) Å, U = 706.8(2) Å3, and Z = 4. In 1, 5-bsa serves as tridentate ligands coordinating to three Ag+ ions through its hydroxyl and bridging ligand carboxyl groups, with the Ag-Ag bonding and two carboxylate ions defined in a slight distorted plane and further extending into a two-dimension layer through the hydroxyl and the overlapping and off-set stacking interactions. In 2, adjacent Ag+ ions via Ag-Ag bonding interactions generate a one-dimension silver chain and adjacent silver chains are further linked by μ2-N, O atoms of 2-aba to result in a two-dimensional configuration, with the inter-chain hydrogen bonding interaction forming a three-dimension supramolecular structure. Both the two silver(I) complexes have strong inhibitory activities against Jack Bean urease with the IC50 values of 21.98 μM for 1 and 25.34 μM for 2, but neglectable inhibition activity on Xanthine Oxidase. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.