In this review article, we address how activity-dependent Ca2+ signaling is crucial for hippocampal synaptic/structural plasticity and discuss how changes in neuronal oxidative state affect Ca2+ signaling and synaptic plasticity. We also analyze current evidence indicating that oxidative stress and abnormal Ca2+ signaling contribute to age-related synaptic plasticity deterioration.
CITATION STYLE
Hidalgo, C., & Arias-Cavieres, A. (2016, May 1). Calcium, reactive oxygen species, and synaptic plasticity. Physiology. American Physiological Society. https://doi.org/10.1152/physiol.00038.2015
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