Identification of the gene encoding the major cellobiohydrolase of the white rot fungus Phanerochaete chrysosporium

Abstract

Previous studies have shown that the cellobiohydrolases of the white rot basidiomycete Phanerochaete chrysosporium are encoded by a family of structurally related genes. In this investigation, we identified and sequenced the most highly transcribed gene, cbhI-4. Evidence suggests that in this fungus the dominant isozyme, CBH1, is encoded by cbh1-4.