InterPregGen: Genetic studies of pre-eclampsia in three continents

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Abstract

Pre-eclampsia is a major cause of maternal and fetal mortality in pregnancy. The identification of genetic variants which predispose to pre-eclampsia demands large DNA collections from affected mothers and babies and controls, with reliable supporting phenotypic data. The InterPregGen study has assembled a consortium of researchers from Europe, Central Asia and South America with the aim of elucidating the genetic architecture of pre-eclampsia. The MoBa collection is playing a vital role in this collaborative venture, which has the potential to provide new insights into the causes of pre-eclampsia, and provide a rational basis for novel approaches to prevention and treatment.

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Morgan, L., McGinnis, R., Steinthorsdottir, V., Svyatova, G., Zakhidova, N., Lee, W. K., … Laivuori, H. (2014). InterPregGen: Genetic studies of pre-eclampsia in three continents. Norsk Epidemiologi, 24(1–2), 141–146. https://doi.org/10.5324/nje.v24i1-2.1815

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