Facile and efficient synthesis of hydrophenanthren-1(2H)-ones and naphtho[2,1-c]furan-3(1H)-ones by a palladium-catalyzed aryne annulation strategy

Abstract

Novel palladium-catalyzed carboannulation reactions of arynes with functionalized vinyl iodides are reported. By applying allyl-substituted iodocycloenones and iodofuranones, a series of hydrophenanthren-1(2H)-ones and naphtho[2,1-c]furan-3(1H)-ones were efficiently constructed in one pot under mild conditions. © 2010 Wiley-VCH Verlag GmbH &Co. KGaA, Weinheim.