In vitro antioxidant, anti-inflammatory, and photoprotective activities of aqueous extract of the endemic plant Hammada scoparia L. from Algeria

Abstract

This study aimed to analyze the chemical profile and evaluate the biological activities of the aqueous extract of H. Scoparia, an endemic plant found in Southeastern Algeria. The aqueous extract was subjected to phytochemical screening, RP-HPLC, and FT-IR analysis. The anti-inflammatory activity was examined using the protein denaturation method, and the photoprotective activity was evaluated using UV-Visible spectrophotometry. The antioxidant activity was assessed using ABTS, DPPH, and FRAP assays. The study found the presence of various secondary metabolites such as polyphenols, tannins, and saponins. This study suggests that H. Scoparia extract has the potential as a natural source of bio-actives for developing drugs. The extract exhibited significant antioxidant activity. The study revealed that H. Scoparia extract demonstrated excellent photoprotective activity against UV, and significant biological activities in vitro.