Clinical observation of tiaojining recipe in combination with corticosterone in infantile primary nephrotic syndrome

Abstract

OBJECTIVE: To investigate the effects of Tiaojining recipe (TJNR) combined with corticosterone (CS) in treating infantile primary nephrotic syndrome (IPNS). METHODS: Sixty inpatients with IPNS were divided into two groups, which consisted of 30 cases as the treated group treated by TJNR combined with CS and 30 cases of the control group were treated by CS alone for 8 weeks. The changes of urinary protein, serum albumin, blood cholesterol, platelet and blood pressure before and after treatment were observed. RESULTS: The total effective rate of the treated group was significantly higher than that of the control group (P < 0.01). The times for urinary protein disappearance of the treated group was significantly shorter than that of the control group (P < 0.05). Compared with the control group. TINR could prevent hypertension, lower lipidemia and platelets (P < 0.01). CONCLUSION: TJNR could enhance the curative effects of CS on IPNS and reduce the side-effects of CS safely and effectively.