Preparation of Carboxylic Acids from Aldehydes (Including Hydroxylated Benzaldehydes) by Oxidation with Chlorite.

Abstract

During the oxidation of aldehydes to acids with sodium chlorite, chlorine dioxide is simultaneously formed and may react with starting material and products in undesirable side-reactions. By performing the reaction in the presence of a chlorine scavenger, e.g. sulphamic acid, the formation of chlorine dioxide is avoided, and high yields of acids from the corresponding aldehydes (even hydroxylated benzaldehydes) are obtanied