Association of airway obstruction, sleep, and phasic abdominal muscle activity after upper abdominal surgery

Abstract

We recorded nasal gas flow, sleep stage, and abdominal muscle EMG pattern in 11 patients throughout the night after abdominal surgery, to examine the association between phasic activity of the abdominal muscles, sleep stage, and flow disturbance. We used a miniaturized data logging system, and obtained satisfactory records in eight patients. The data were divided into 30-s epochs. Each epoch was classified as either awake or asleep. The epochs were also classified for the presence of phasic activity in the external oblique abdominal muscle, and for evidence of airway obstruction. Association between these features was tested by a quasi likelihood log linear model. Values given are median (quartiles) for the eight subjects. Sleep occurred for 62 (46-69)% of the study time. During sleep, inspiratory flow was normal for 69 (48-81)% of the time, whereas during wakefulness, the flow pattern was normal for 51 (28-77)% of the time. Phasic activity was present 16 (12-25)% of the time during sleep and 24 (19-37)% of the time during wakefulness (P<0.001). In the awake state, when breathing was normal, phasic activity was present 16 (11-30)% of the time. When breathing was obstructed, phasic activity was present 38 (25-44)% of the time (P<0.001). These surprising findings suggest that sleep may be seriously disturbed by airway obstruction, so that a stable sleep state is not reached. We could not confirm previous findings that disturbed breathing in post-operative patients only occurs during sleep.