How to Manage Opioid-Related Constipation in Individuals with Chronic Nonmalignant Pain Syndromes

Abstract

ORC represents a spectrumof disorders differentiated by the onset of constipation symptoms as they relate to opioid initiation and dosing and can be functionally classified as OIC and OEC, representing 2 separate entities.These entities should be differentiated to promote optimal opportunities for adequate symptom control. Practitioners, especially those in the GI field, should be aware of these differences because initial treatment failures (especially in patients withOEC) are likely to be referred to our clinical practices.