Pulmonary blastoma

Abstract

Pulmonary blastoma is now accepted as a distinctive neoplasm. It remains rare, and only 28 cases have been reliably recorded. A further 2 cases are reported, and the previous literature is reviewed. There are no specific clinical or radiologic features of pulmonary blastoma. The presentation can be that of any other pulmonary tumor although a peripheral situation is usual and a large size is often attained before detection. Pulmonary blastoma is a mixed tumor with malignant epithelial and connective tissue components with a distinctive resemblance to fetal lung. The treatment of choice is surgical excision and the overall prognosis is poor. It is doubtful whether the tumor has a true blastomatous origin.