Botulinum toxoid in the management of gustatory sweating (Frey's syndrome) after superficial parotidectomy

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Abstract

Botulinum toxin has been successfully used to treat Frey's syndrome occurring in a 31-year-old patient following superficial parotidectomy for pleomorphic adenoma. An initial injection of 7.5 U (0.3 ml over 6 cm2 of cheek) resulted in 3 months' resolution of gustatory sweating and flushing and a second injection 12 months' symptomatic improvement. The symptoms recurred after further facial surgery.

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Birch, J. F., Varma, S. K., & Narula, A. A. (1999). Botulinum toxoid in the management of gustatory sweating (Frey’s syndrome) after superficial parotidectomy. British Journal of Plastic Surgery, 52(3), 230–231. https://doi.org/10.1054/bjps.1998.3058

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