Background: The present study was performed to investigate the incidence of early postoperative cognitive dysfunction (POCD) after non-coronary bypass surgery and the potential risk factors in Chinese population.Methods: We performed a prospective study in a teaching tertiary hospital from May 2012 to August 2012. One hundred and seventy-six adult patients undergoing non-coronary bypass surgery were recruited. Mini-Mental State Examination (MMSE) score was evaluated before and 3 to 5 days after surgery. Patients with a MMSE score reduction of 2 was diagnosed with POCD.Results: The general incidence of POCD was 33.0%, with no significant difference between the types of surgeries. In the univariate analysis, POCD associated factors included age, duration of surgery, anesthesia, cardiopulmonary bypass (CPB), cross-clamp and rewarming, and sevoflurane concentration. However, only age, cross-clamp duration and sevoflurane concentration were demonstrated to be independent risk factors for POCD.Conclusion: Incidence of early POCD after non-coronary bypass surgery was relatively high in Chinese population. Advanced age, longer aortic cross-clamp duration and lower sevoflurane concentration was associated with a higher incidence of POCD. © 2013 Xu et al.; licensee BioMed Central Ltd.
CITATION STYLE
Xu, T., Bo, L., Wang, J., Zhao, Z., Xu, Z., Deng, X., & Zhu, W. (2013). Risk factors for early postoperative cognitive dysfunction after non-coronary bypass surgery in Chinese population. Journal of Cardiothoracic Surgery, 8(1). https://doi.org/10.1186/1749-8090-8-204
Mendeley helps you to discover research relevant for your work.