Shape and Facet Analyses of Alveolar Airspaces of the Lung

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Abstract

Changes in lung volume during the breathing cycle and also lung diseases are likely to deform even the smallest airspace units, the alveoli. This study reports general ideas to investigate such changes with 3D digital image processing. It comprises morphological characterizations like volume and surface, an evaluation of the angle distribution between facets formed by the septal walls, the number of neighboring alveoli and a shape analysis of the alveolar airspace. The software used is open-source and custom programs are available at: http://github.com/romangrothausmann/.

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Grothausmann, R., Mühlfeld, C., Ochs, M., & Knudsen, L. (2018). Shape and Facet Analyses of Alveolar Airspaces of the Lung. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 11167 LNCS, pp. 49–64). Springer Verlag. https://doi.org/10.1007/978-3-030-04747-4_5

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