AKTIVITAS ANTIOKSIDAN DAN TOKSISITAS EKSTRAK KULIT KAYU RARU (COTYLELOBIUM SP.)

Abstract

Research on natural medicinal plants has been growing due to the increasing interest to natural medicinal material that is considered safer than synthetic medicines. In North Sumatera, bark of sp which is locally known as raru, has been widely utilized by the local community. The skin bark of this species is commonly used as a mixture of "nira" to produce "tuak" (Batak's traditional alcoholic liquor). In addition, local community has been using this species for traditional healing as well. This research is to study the potency of raru's skin bark in producing antioxidant using DPHH method. The toxicity activity of the material was also examined using Brine Shrimp Lethality Test (BSLT) method. Results show that the yield extract of Cotylelobium melanoxylon Pierre was 30.11% and Cotylelobium lanceolatum Craib was 14.50%. Both extracts contains flavonoid, tanin, saponin, triterpenoid and hidroquinon.