Added catalyst-free, versatile and environment beneficial bromination of (hetero)aromatics using NBS in WEPA

Abstract

Abstract: The aromatic or heteroaromatic bromides are the quite common substrates in several organic transformations. The synthesis of arylbromides is challenging and required expensive catalytic systems or problematic organic solvents. This article unveils an environment beneficial, versatile and facile procedure for the synthesis of aryl/heteroaryl bromides using N-bromosuccinimide in water extract of pomegranate ash. The preparation of bromoarenes or bromoheteroarenes was accomplished under atmospheric conditions in the absence of added catalyst, promoter, problematic solvent and additives. The products were formed with greater rates in very high to quantitative yields using biowaste derived media shows the environmental benefits like utilization of waste, safer media, rich chemical economy, economic feasibility and dwindling the chemical waste, has eventual scope towards further explorations. Graphic abstract: [Figure not available: see fulltext.].