Platelet transfusion prophylaxis for patients with haematological malignancies: Where to now?

Abstract

National guidelines for platelet transfusion in many countries recommend that the general platelet transfusion trigger for prophylaxis is 10 × 109/l. This annotation reviews the evidence for this threshold level and discusses other current unresolved issues relevant to platelet transfusion practice such as the optimal dose and the clinical benefit of a strategy for the prophylactic use of platelet transfusions when the platelet count falls below a given threshold. © 2005 Blackwell Publishing Ltd.