Cyclosporine

Abstract

Cyclosporine is effective for atopic dermatitis from the viewpoint of EBM, and has been widely applied in Europe and other countries. A prompt improvement is expected by cyclosporine due to its strong immunity control action. Cyclosporine has a good indication for the patient who is in erythrodermic condition or resistant to topical steroids showing lichenification and prurigo like nodules, or has topical side effect such as skin atrophy, capillary enhance and steroid purpura. Cyclosporine, which has the different action mechanism from steroid, is of great value for the treatment of atopic dermatitis although carefulness is required for long term administration, and it will be necessary to clarify the location of the cyclosporine in the treatment guideline for atopic dermatitis in the future.