Magnitude of Diabetes Comorbidity among People Living with HIV: A Systematic R eview

Abstract

Although the clinical relationship between HIV/AIDS and Diabetes is well established, there is a little summarized evidence about the magnitude ofDiabetescomorbidity among people living with HIV.The aim of this study was to summarizeevidence on the incidence and prevalence of Diabetes comorbidityamong people living with HIV.A systematic review of the incidence and prevalence of Diabetes comorbidity among people living with HIV was conducted. Studies reporting incidence and/orprevalence of diabetes among people living with HIV were retrieved from Embase and Medline databases. Selection of the studieswas based on both relevance and quality.Study and outcome characteristics, were ext racted using a standardized checklist. Resulted were presented using narrative and graphic summaries. PRISMA checklist was used as a guide for reporting of the review results. A total of 12 studies met the inclusion and quality. In total of 43,296 people living with HIV, 1,144 incident cases of diabetes were identified over 174,574 person-years. The incidence rates of diabetes comorbidity as reported by these studies ranged from 5.72 to 23.8 per 1000 person-years. Similarly, a total of 1,724 prevalent cases of diabetes were identified among 41,068 people living with HIV. The reported prevalence rates ranged from 2.85% to 14.9%. High level of variability in the reported incidence and prevalence rates of diabetes comorbidity was observed. Generally, the findings are not in favour of a significantly increased magnitude of diabetes comorbidity in HIV