MALDI-TOF mass spectrometric profiling of spider venoms

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Abstract

Fingerprinting by means of matrix-assisted laser desorption-ionization time-of-flight mass spectrometry (MALDI-TOF MS) represents a tool for rapidly detecting proteinaceous compounds from spider venoms. Here we describe an optimized protocol and discuss methodological details with the aim of providing a platform for obtaining the most informative and reproducible mass spectral data.

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Šedo, O., Pekár, S., & Zdráhal, Z. (2020). MALDI-TOF mass spectrometric profiling of spider venoms. In Methods in Molecular Biology (Vol. 2068, pp. 173–181). Humana Press Inc. https://doi.org/10.1007/978-1-4939-9845-6_9

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