Activation of γ-aminobutyrate production by chloroplastic H 2O2 is associated with the oxidative stress response

Abstract

We isolated an Arabidopsis knockout line lacking glutamate decarboxylase 1(GAD1), one that produced γ-aminobutyrate (GABA), as an oxidative stress-insensitive mutant, and found that chloroplastic H2O 2 enhances GAD1 expression and GABA levels. This suggests a possible relationship between GABA metabolism and the chloroplastic H2O 2-mediated stress response.