There is limited understanding of the specific role of high-density lipoprotein cholesterol (HDL-C) in the development of various age-related ocular diseases, despite it being a common measurable biomarker in lipid profiles. This literature review summarizes current knowledge of the role of HDL-C, if any, in pathogenesis and progression of four age-related ocular diseases, namely age-related macular degeneration (AMD), age-related cataract, glaucoma, and diabetic retinopathy (DR), and will primarily discuss epidemiological and genetic evidence.
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CITATION STYLE
Betzler, B. K., Rim, T. H., Sabanayagam, C., Cheung, C. M. G., & Cheng, C. Y. (2020, April 1). High-density lipoprotein cholesterol in age-related ocular diseases. Biomolecules. MDPI AG. https://doi.org/10.3390/biom10040645