Synergy of concurrent low dose oxamniquine and praziquantel in schistosomiasis

Abstract

Laboratory studies suggest that concurrent low dose administration of oxamniquine (Vansil) and praziquantel (Biltricide) is likely to be highly effective in the single dose treatment of schistosomiasis. We have conducted a dose finding study of this coadministration regimen in Schistosoma haematobium and S. mansoni infections.