Effects of Luo Han Guo on throat complications associated with tracheal intubation: a randomized controlled trial

Abstract

Objectives: Conventional treatment for throat complications after surgery involves the use of hormone therapy, which has variable effects. This study was performed to investigate the effects of oral administration of Luo Han Guo decoction for throat complications after tracheal intubation during general anesthesia for laparoscopic radical hysterectomy. Methods: Beginning at 6 h after surgery, patients in the experimental group were administered 30 mL of a Luo Han Guo decoction; the control group received black tea. Patients in both groups were evaluated using a Visual Analogue Scale for the degree of throat soreness at 2, 12, 24, and 48 h after surgery; coughing and expectoration were evaluated at 48 h after surgery. Results: This study included 203 patients: 102 in the experimental group and 101 in the control group. Compared with controls, the experimental group had significantly lower evaluation scores at 12, 24, and 48 hours postoperatively. Moreover, at 48 hours postoperatively, coughing and expectoration were significantly reduced in the experimental group, compared with in the control group. Conclusions: Administration of a Luo Han Guo decoction can effectively reduce throat pain, hoarseness, throat swelling, cough, and sputum after tracheal intubation during general anesthesia.