The value of admission HbA 1c level in diabetic patients with acute coronary syndrome

17Citations
Citations of this article
47Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Background: Elevated admission glucose level is a strong predictor of short-term adverse outcome in patients with acute coronary syndrome (ACS). However, the prognostic value of diabetic control (ie, hemoglobin A 1c levels) in patients with ACS is still undefined. Hypothesis: Hemoglobin A 1c level may predict short-term outcome in patients with ACS. Methods: We conducted a retrospective study with prospective follow-up in 317 diabetic patients with ACS. Patients were stratified into 2 groups based on HbA 1c level, checked within 8 weeks of the index admission (optimal control group, HbA 1c ≤ 7% suboptimal control group, HbA >7%). All patients were followed up prospectively for major adverse cardiovascular events (MACE) and mortality for 6 months. Short-term clinical outcomes were also compared between the 2 study groups. Results: In our cohort, 27.4%, 46.4%, and 26.2% patients had unstable angina, non-ST-segment elevation myocardial infarction, and ST-segment elevation myocardial infarction, respectively. In-hospital mortality was similar in both HbA groups (3.37% vs 2.88%, P = 0.803). Six-month MACE was also similar (26.40% vs 26.47%, P = 0.919). All-cause mortality, cardiovascular mortality, symptom-driven revascularization, rehospitalization for angina, and hospitalization for heart failure were also similar in both groups. The hazard ratios for 6-month MACE and individual endpoints were also similar in both groups. Conclusions: This study suggests that HbA 1c levels before admission are not associated with short-term cardiovascular outcome in diabetic patients subsequently admitted with ACS. © 2011 Wiley Periodicals, Inc.

Cite

CITATION STYLE

APA

Chan, C. Y., Li, R., Chan, J. Y. S., Zhang, Q., Chan, C. P., Dong, M., … Yu, C. M. (2011). The value of admission HbA 1c level in diabetic patients with acute coronary syndrome. Clinical Cardiology, 34(8), 507–512. https://doi.org/10.1002/clc.20915

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free