Trichothecene mycotoxins are secondary metabolites of Fusarium moulds that routinely infect cereal crops. Processing can reduce, but not eliminate, trichothecenes from cereal-based foods, and the potential presence of the trichothecenes in cereal foods poses a significant health risk to consumers. Deoxynivalenol (vomitoxin, DON) is the most common of the trichothecenes detected in cereal crops and is subject to government regulation in many countries. Sensitive (ng/g) methods for the detection of trichothecenes in cereal grains and food products are needed to protect consumers, to provide data for dietary exposure estimates, and to support research into the control of moulds and subsequent toxin production. Laboratories require simple, rugged and reliable methods for routine testing, with unequivocal identification of suspect mycotoxins. A method employing gas chromatography-negative ion chemical ionisation / mass spectrometry (GC-NICI/MS) has been developed and used for the routine determination of eight of the most significant trichothecenes in a variety of commodities. This chapter discusses GC, liquid chromatographic (LC) and supercritical fluid chromatographic methods that are currently used for the analysis of trichothecene mycotoxins.
CITATION STYLE
Lombaert, G. A. (2002). Methods for the determination of deoxynivalenol and other trichothecenes in foods. In Advances in Experimental Medicine and Biology (Vol. 504, pp. 141–153). Kluwer Academic/Plenum Publishers. https://doi.org/10.1007/978-1-4615-0629-4_14
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