Serotonin (5-HT) is a neuromodulator that has been attributed to cost assessment and harm aversion. In this review, we look at the role 5-HT plays in making decisions when subjects are faced with potential harmful or costly outcomes. We review approaches for examining the serotonergic system in decision-making. We introduce our group's paradigm used to investigate how 5-HT affects decision-making. In particular, our paradigm combines techniques from computational neuroscience, socioeconomic game theory, human-robot interaction, and Bayesian statistics. We will highlight key findings from our previous studies utilizing this paradigm, which helped expand our understanding of 5-HT's effect on decision-making in relation to cost assessment. Lastly, we propose a cyclic multidisciplinary approach that may aid in addressing the complexity of exploring 5-HT and decision-making by iteratively updating our assumptions and models of the serotonergic system through exhaustive experimentation. © 2013 Asher, Craig, Zaldivar, Brewer and Krichmar.
CITATION STYLE
Asher, D. E., Craig, A. B., Zaldivar, A., Brewer, A. A., & Krichmar, J. L. (2013, November 21). A dynamic, embodied paradigm to investigate the role of serotonin in decision-making. Frontiers in Integrative Neuroscience. https://doi.org/10.3389/fnint.2013.00078
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