Chiral Amino Acids-Derived Catalysts and Ligands

Abstract

Transforming amino acids into novel catalysts and ligands is a remarkable subset of new catalyst development in order to imitate enzymatic efficiencies. Their ability to perform a variety of asymmetric catalytic reactions is complimented by their ready availability, rich transformations, stability and easy procedure. Herein, we focused on describing our endeavor of developing new catalysts and ligands from primary and secondary amino acids. It includes C2-symmetric N,N'-dioxides, guanidine-amides, bispidine-based diamines, and other organic salts. The account covered a brief introduction about their discovery, representative applications and related mechanisms.