bHenoch-Schonlein Purpura (HSP) is a small vessel vasculitis mediated by IgA-immune complex deposition. It is characterized by the clinical tetrad of non-thrombocytopenic palpable purpura, abdominal pain, arthritis and renal involvement. Pathologically, it can be considered a form of immune complex-mediated leukocytoclastic vasculitis (LCV) involving the skin and other organs. Though it primarily affects children (over 90% of cases), the occurrence in adults has been rarely reported. Management often involves the use of immunomodulatory or immune-suppressive regimens. © 2011 Jithpratuck et al; licensee BioMed Central Ltd.
CITATION STYLE
Jithpratuck, W., Elshenawy, Y., Saleh, H., Youngberg, G., Chi, D. S., & Krishnaswamy, G. (2011, May 27). The clinical implications of adult-onset henoch-schonelin purpura. Clinical and Molecular Allergy. https://doi.org/10.1186/1476-7961-9-9
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