Abstract
7-Ketocholesterol (7-Kchol, oxidized cholesterol) is an important mediator of cell death in atherosclerosis mediated by up-regulated Nox 4 gene expression. In the current study using the human colon cancer HT-29 cell line, we have demonstrated that 7-Kchol promotes endoplasmic reticulum (ER) stress via gene up-regulation of ER chaperone and membrane kinases. © 2009 Verlag der Zeitschrift für Naturforschung Tübingen.
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Lee, W. H., Lee, C. S., Kwon, K., Kwon, Y. S., Kim, S. W., Goo, T. W., & Kwon, O. Y. (2009). 7-ketocholesterol induces endoplasmic reticulum stress in HT-29 cells. Zeitschrift Fur Naturforschung - Section C Journal of Biosciences, 64(3–4), 307–310. https://doi.org/10.1515/znc-2009-3-425
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