Abstract
Nuclease-based genome editing has proven to be a powerful and promising tool for disease modeling and gene therapy. Recent advances in CRISPR/Cas and TALE indicate that they could also be used as a targeted regulator of gene expression, as well as being utilized for illuminating specific chromosomal structures or genomic regions.
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Deng, L., Ren, R., Wu, J., Suzuki, K., Izpisua Belmote, J. C., & Liu, G. H. (2015). CRISPR/Cas9 and TALE: beyond cut and paste. Protein and Cell, 6(3), 157–159. https://doi.org/10.1007/s13238-015-0137-5
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