Small angle neutron scattering (SANS) allows studying bio-macromolecular structures and interactions in solution. It is particularly well-suited to study structural properties of intrinsically disordered proteins (IDPs) over a wide range of length-scales ranging from global aspects (radii of gyration and molecular weight) down to short-distance properties (e.g., cross-sectional analysis). In this book chapter, we provide a practical guide on how to carry out SANS experiments on IDPs and discuss the complementary aspects and strengths of SANS with respect to small angle X-ray scattering (SAXS). © 2012 Springer Science+Business Media New York.
CITATION STYLE
Gabel, F. (2012). Small angle neutron scattering for the structural study of intrinsically disordered proteins in solution: A practical guide. Methods in Molecular Biology, 896, 123–135. https://doi.org/10.1007/978-1-4614-3704-8_8
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