Abstract
The purpose of this review is to examine experimental information concerning the structure and function of the G protein-coupled serotonin receptors in the three-dimensional context provided by the structure of rhodopsin. A critical examination of the suitability of rhodopsin as a template for serotonin receptor modeling from the level of sequence alignment to interpretation of biochemical experiments of relevance to the issues of structure-function relationships is presented.
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CITATION STYLE
Westkaemper, R. B., & Roth, B. L. (2008). Structure and Function Reveal Insights in the Pharmacology of 5-HT Receptor Subtypes. In The Serotonin Receptors (pp. 39–58). Humana Press. https://doi.org/10.1007/978-1-59745-080-5_2
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