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Genomic and Phenotypic Characterization of the Nontoxigenic Clostridioides difficile Strain CCUG37785 and Demonstration of Its Therapeutic Potential for the Prevention of C. difficile Infection

  • Wang S
  • Heuler J
  • Wickramage I
  • et al.
Microbiology Spectrum (2022) 10(2)
DOI: 10.1128/spectrum.01788-21
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Abstract

Clostridioides difficile infection (CDI) symptoms range from diarrhea to intestinal inflammation/lesion and death and are mainly caused by two exotoxins, TcdA and TcdB. Active vaccination provides the attractive opportunity to prevent CDI and recurrence.

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Wang, S., Heuler, J., Wickramage, I., & Sun, X. (2022). Genomic and Phenotypic Characterization of the Nontoxigenic Clostridioides difficile Strain CCUG37785 and Demonstration of Its Therapeutic Potential for the Prevention of C. difficile Infection. Microbiology Spectrum, 10(2). https://doi.org/10.1128/spectrum.01788-21

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