A monoclonal antibody which blocks infection with feline immunodeficiency virus identifies a possible non-CD4 receptor

  • Hosie M
  • Willett B
  • Dunsford T
  • et al.
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Abstract

Monoclonal antibody vpg15 detects a 24-kDa cell surface protein on feline cells permissive for infection with feline immunodeficiency virus (FIV). The antibody blocks infection of FIV-susceptible cells, and expression of the vpg15 marker is decreased in FIV-infected cells in vitro. These results suggest that the antibody may recognize an FIV receptor distinct from CD4.

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Hosie, M. J., Willett, B. J., Dunsford, T. H., Jarrett, O., & Neil, J. C. (1993). A monoclonal antibody which blocks infection with feline immunodeficiency virus identifies a possible non-CD4 receptor. Journal of Virology, 67(3), 1667–1671. https://doi.org/10.1128/jvi.67.3.1667-1671.1993

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