Chiral organocatalyzed intermolecular Rauhut–Currier reaction of nitroalkenes with ethyl allenoate

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Abstract

An enantioselective intermolecular Rauhut–Currier (RC) reaction of nitroalkenes with ethyl allenoate has been established with quinidine-derived β-isocupreidine. The present RC reaction afforded α-functionalized allenoates 3 in up to 94% yield with 59% enantiomeric excess (ee).

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APA

Takizawa, S., Sako, M., Kishi, K., Shigenobu, M., Vo-Thanh, G., & Sasai, H. (2017). Chiral organocatalyzed intermolecular Rauhut–Currier reaction of nitroalkenes with ethyl allenoate. Chemical and Pharmaceutical Bulletin, 65(11), 997–999. https://doi.org/10.1248/cpb.c17-00554

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