Tissue engineering and regenerative medicines: An interdisciplinary understanding

Abstract

Tissue damage caused by disease or trauma necessitates a substitution of the damaged tissue through tissue engineering and regenerative medicine. It is a multidisciplinary research in the field of tissue engineering that deals with the synthesis of various kinds of human tissue equivalents, such as heart muscle, bone, cartilage, blood vessels, and nerves. It potentially leads to entire organ replacement by employing principles from the biology (molecular, cell biology, physiology, immunology, chemical) and engineering (electrical, materials science, mechanical) domains. The development of stem cells has opened a vast realm for regenerative medicines, tissue, and organs. Tissue engineering and regenerative medicines adopt the evaluation of biomaterial performance and behavior. The evaluation of properties also includes its drug delivery nature and biomimetic properties. The condemnatory hurdle in tissue engineering and regenerative medicine lies in understanding the interaction between the cells and engineered tissues, the influence of physical and chemical stimuli on cell growth, and cell function, migration, and differentiation. This chapter is a comprehensive discussion on interdisciplinary involvement in tissue engineering and regenerative medicines.