Palladium-catalyzed aryl-aryl bond formation through double C-H activation.

Abstract

Aryl-aryl bond formation constitutes one of the most important subjects in organic synthesis. The recently developed direct arylation reactions for the formation of aryl-aryl bond have emerged as very attractive alternatives to traditional cross-coupling reactions. Particularly, the direct arylation through double C-H activation using the simple arenes as both coupling partners is a highly economic and attractive method. In this chapter, the recent progress of Pd-catalyzed aryl-aryl oxidative coupling reactions through double C-H activation is presented.