Resilience as a Measure of Outcome and Recovery in Schizophrenia

Abstract

This chapter is a clinical overview of resilience as a measure of outcome and recovery in schizophrenia. The chapter starts with an elucidation of the concept of resilience as applied in psychiatry. The basic neurobiology of resilience and resilience as a psychobiological construct for the pathogenesis of psychiatric disorders is discussed. This is followed by a discussion of specific factors in the neurobiology and genetics of mechanisms that enhance resilience and also play a role in the recovery from schizophrenia. Studies in the realm of schizophrenia and resilience (both long term and short term) and neuroimaging data are discussed, and certain points of relevance from a clinical perspective for resilience and recovery from schizophrenia are discussed.