This study presents three novel integrons In1394, In1395, and In1443, three novel unit transposons Tn6392, Tn6393, and Tn6403, one novel conjugative element (ICE) Tn6413, and the first sequenced IncP-7 resistance plasmid p1160-VIM from clinical Pseudomonas aeruginosa. Detailed sequence comparison of p1160-VIM (carrying Tn6392 and Tn6393) and Tn6413 (carrying Tn6403) with related elements were performed. Tn6392, Tn6393, and Tn6403 were generated from integration of In1394 (carrying blaVIM-24), In1395 and In1443 (carrying blaVIM-24) into prototype Tn3-family unit transposons Tn5563, Tn1403, and Tn6346, respectively. To the best of our knowledge, this is the first report of a blaVIM-24-carrying P. aeruginosa isolate.
CITATION STYLE
Zeng, L., Zhan, Z., Hu, L., Jiang, X., Zhang, Y., Feng, J., … Zhou, D. (2019). Genetic characterization of a blaVIM-24-Carrying IncP-7ß plasmid p1160-VIM and a blaVIM-4-harboring integrative and conjugative element Tn6413 from clinical pseudomonas aeruginosa. Frontiers in Microbiology, 10(FEB). https://doi.org/10.3389/fmicb.2019.00213
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