Context: Inflammatory bowel disease causes physical and psychosocial consequences that can affect the health related quality of life. Objectives: To analyze the relationship between clinical and sociodemographic factors and quality of life in inflammatory bowel disease patients. Methods: Ninety two patients with Crohn’s disease and 58 with ulcerative colitis, filled in the inflammatory bowel disease questionnaire (IBDQ-32) and a questionnaire to collect sociodemographic and clinical data. The association between categorical variables and IBDQ-32 scores was determined using Student t test. Factors statistically significant in the univariate analysis were included in a multivariate regression model. Results: IBDQ-32 scores were significantly lower in female patients (P<0.001), patients with an individual perception of a lower co-workers support (P<0.001) and career fulfillment (P<0.001), patients requiring psychological support (P = 0.010) and pharmacological treatment for anxiety or depression (P = 0.002). A multivariate regression analysis identified as predictors of impaired HRQOL the female gender (P<0.001) and the perception of a lower co-workers support (P = 0.025) and career fulfillment (P = 0.001). Conclusion: The decrease in HRQQL was significantly related with female gender and personal perception of disease impact in success and social relations. These factors deserve a special attention, so timely measures can be implemented to improve the quality of life of patients.
Magalhães, J., de Castro, F. D., Carvalho, P. B., Leite, S., Moreira, M. J., & Cotter, J. (2014). Quality of life in patients with inflammatory bowel disease: Importance of clinical, demographic and psychosocial factors. Arquivos de Gastroenterologia, 51(3), 192–197. https://doi.org/10.1590/S0004-28032014000300005