Holt oram syndrome

Abstract

Holt Oram Syndrome, an autosomal dominant disorder is constellation of congenital heart diseases and skeletal abnormalities. Amongst the congenital heart defects ostium secundum type of atrial septal defect is most common. Electrocardiographic abnormalities include heart blocks and AV conduction defects up to variable extent. In addition to cardiac abnormalities skeletal abnormalities such as radial dysplasia or hypoplasia and other upper limb abnormalities have been reported. We are presenting a case 25 years old lady with Holt Oram syndrome presenting with cardiac failure.