Risk factors for neonatal hyperbilirubinemia: a case control study

Abstract

Background: Neonatal Hyperbilirubinemia is one of the most common reasons for NICU admissions. The frequency of neonatal jaundice has been on an increase since the last decade. Is the increase due to changes in obstetric practice or drugs? There is no definite reason. This study was undertaken to find out any obstetric characteristics which may contribute to the development of Neonatal Hyperbilirubinemia and which is modifiable.Methods: Record review data from 140 singleton deliveries at the Institute of Maternal & Child Health ,Govt. Medical College, Kozhikode, Kerala were analyzed to determine the relationship between neonatal hyperbilirubinemia (>10mg/dl) and maternal characteristics. Confounding variables were controlled by multiple logistic regression analysis.Results: There was statistically significant relationship between hyperbilirubinemia and LBW, preterm delivery, PPROM, breast feeding, neonatal infection, instrumental delivery and presence of GDM and IUGR.Conclusions: By identifying these obstetric characteristics, we may be able to modify them and reduce the need for NICU admissions for Neonatal Hyperbilirubinemia.