Oxidant markers and their impact on antioxidant status and erythrocyte fragility in theileriasis in calves

Abstract

The present study has been carried out on the calves less than one month of age suffering from clinical Theileriosis. All the cases came to Referral veterinary polyclinic, IVRI, Izatnagar, Bareilly for treatment during 2015. Erythrocytic LPO in clinically affected calves were significantly (P<0.05) higher than healthy animals. GSH, and SOD values in ailing calves were significantly (P<0.05) lower than healthy control and postreated calves. Catalase was also higher in infected calves but non significant. The hemoglobin concentration was significantly (P<0.05) lower in ailing animals. The erythrocyte fragility at 0.9%, 0.8% and 0.6% NaCl concentration was significantly (P<0.05) higher than the control group. However, there were less erythrocytic fragility observed in NaCl 0.4% and 0.2% concentration in infected animals. In conclusion, anemia occurs in Theileria annulata infection is due to corpuscular oxidative damage as revealed from lipid peroxidation and antioxidant status which contribute to RBC fragility and consequent anemia.