Histologic and Clinical Evaluation of a Bioactive Calcium Phosphosilicate Bone Graft Material in Postextraction Alveolar Sockets

Abstract

Background: Long-term success of dental implants has been demonstrated when placed simultaneously with or after a socket grafting procedure. Although optimal bone formation can be from 6 to 9 months or longer with grafting materials other than autogenous bone, utilization of bone allograft eliminates patient morbidity through elimination of autograft harvest sites. Methods: This study evaluated bone formation following grafting of 22 post-extraction alveolar sockets with bioactive calcium phos-phosilicate putty (CPS Putty) graft material. Results: At 5-6 months post grafting there was bone regeneration showing both normal clinical attributes and radiographic trabecu-lar appearance. Histomorphometric analysis revealed average vital bone content of 48.2% ± 6.8 to residual graft content of 2.4% ± 1.4 for the 22 sockets in the study, at an average healing period of 5.4 months ± 1.5. Conclusions: The high percentage of vital bone content, after a relatively short healing phase, suggests that CPS Putty can be a reliable choice for osseous regeneration in cases of crest preservation and implant related surgeries. Abstract KEY