Risk of High-Grade Malignancy (ROHM)

Abstract

Based on the premise of The Paris System for Reporting Urinary Cytology (TPS), that the main goal of urine cytology is the detection of clinically significant cancers, particularly high-grade urothelial carcinoma, a new term is coined: risk of high-grade malignancy (ROHM) for each diagnostic category. The reported experience after the implementation of TPS classification worldwide has shown an increased sensitivity in urinary cytology, along with progressively higher ROHM across the diagnostic categories, resulting in updated numbers to the original values cited in the first edition of TPS. These results reflect many publications that reported varied geographic experiences in hospitals and clinical laboratories following the adoption of TPS since its initial publication in 2016.