Pathology of Breast Cancer

Abstract

In this chapter, pathological features of breast carcinoma are discussed. Classification is based on the recent WHO classification of breast carcinoma, and specific gross and microscopic features of in situ and invasive breast carcinomas are explained. Morphological groups, grading of DCIS, and the necessary information that should be in a surgical pathology report are discussed. Recent information about columnar cell lesions and flat epithelial atypia of the breast are discussed, along with their clinical importance. Atypical lobular hyperplasia and lobular carcinoma in situ (LCIS) are discussed under the heading “lobular neoplasia.” Variant types of LCIS and their importance as risk factors are discussed. Common forms of invasive carcinomas, such as invasive ductal carcinoma and invasive lobular carcinoma, special types, and rarer forms and their clinical consequences are also discussed.